Dapsone Hypersensitivity or Viral Exanthem?
نویسندگان
چکیده
منابع مشابه
Dapsone hypersensitivity syndrome masquerading as a viral exanthem: three cases and a mini-review.
INTRODUCTION We report 3 cases of dapsone hypersensitivity syndrome due to anti-malarial chemoprophylactic treatment with maloprim, in military servicemen, presenting like a viral exanthem. CLINICAL PICTURE Three male military recruits presented with fever and rash, 6 to 8 weeks after commencing on weekly doses of maloprim. TREATMENT A course of topical and systemic corticosteroids and oral...
متن کاملSevere dapsone hypersensitivity syndrome.
Dapsone, a potent antiparasitic and anti-inflammatory compound, is mainly used in the treatment of leprosy and a variety of blistering skin diseases. It may cause a severe adverse drug reaction with multiorgan involvement known as dapsone hypersensitivity syndrome. We report the case of a 21-year-old female patient with dapsone hypersensitivity syndrome. The clinical presentation mimicked a vir...
متن کاملDapsone hypersensitivity syndrome with myocarditis.
Drug hypersensitivity with myocarditis is known to occur with many drugs especially with antiepileptics, sulpha-compounds and daposne. Dapsone (4, 4 diaminodiphenyl sulphone) induced hypersensitivity is known to occur in about 2% of leprosy patients on treatment and an incidence of 1.66% in non-leprosy patients. We report this rare case of dapsone hypersensitivity syndrome in a girl on dapsone ...
متن کاملReinstatement of dapsone following hypersensitivity.
Sir, Dapsone therapy can cause severe adverse reactions known as the sulphone or dapsone hypersensitivity syndrome (DS). The most common presenting symptom is a maculopapular or exfoliative rash confined to either the upper limbs or the forehead, but it can also be disseminated. The sequence of symptoms – dermatitis, lymphadenopathy notably along the posterior border of the sternomastoid muscle...
متن کاملSevere dapsone hypersensitivity syndrome in a child
Dapsone (4,4'-diaminodiphenylsulfone, DDS), a potent anti-inflammatory agent, is widely used in the treatment of leprosy and several chronic inflammatory skin diseases. Dapsone therapy rarely results in development of dapsone hypersensitivity syndrome, which is characterized by fever, hepatitis, generalized exfoliative dermatitis, and lymphadenopathy. Here, we describe the case of an 11-year-ol...
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ژورنال
عنوان ژورنال: Acta Dermato-Venereologica
سال: 2004
ISSN: 0001-5555
DOI: 10.1080/00015550410026407